When a priest disappears Jack begins to think that the man is involved in some wrongdoing rather than the possible victim of a crime.

A missing-persons case becomes a criminal investigation when, after a recently engaged woman disappears, it turns out that she was running a confidence scheme.

When a 14-year-old violinist disappears on the night of a concert, the team follows her and her valuable violin’s trail and Samantha bravely tries to recover from the gunshot wound.

Malone searches for a missing woman whose description matches those of a series of murder victims from a 12-year-old case only to learn that Graham Spaulding is pulling the strings, and drawing on incidents in Jack’s past to lure him into a trap.

When a high school sex-scandal leads to murder it is the team’s job to figure out who did it and why.

The team is baffled as to why no family members come forward after a Latino boy is abducted in middle of the day time from a street in Spanish Harlem. That leads the team to suspect that his family are illegal immigrants and are too afraid to come forward.

When a young fireman disappears after heroically pulling two people from a burning building, the team begins to suspect that other firemen may be guilty of arson.

The team searches for a doctor who disappeared after going for a run with her ex-husband. They soon find out she recently had a miscarriage and broke up with her boyfriend.

When Luke Horton disappears after a class reunion, the team initiates a search for him, and learn that Luke was living a double life and was finally ready to come clean.

The team has a wealth of suspects from which to choose as they search for a missing paparazzo who felt responsible when one of his pictures outing a TV star led to the actor’s ruin and eventual suicide, and vowed to redeem himself and his career by helping an environmental watchdog group expose a corporation’s [...]

The team searches for a missing criminal defense attorney. While investigating the man’s life, Jack begins to believe that his recent behavior is the result of paranoid schizophrenia.

The team search for a missing motivational speaker only to find that there is an abundance of suspects. During the investigation they find out that the man is not who he appears to be.

When a female ex-cop-turned-bounty-hunter is shot and goes missing, the team must investigate her whereabouts.

Eric Miller seems like the average twelve-year-old, but the clues found at the scene suggest that he may have been abducted. After the team learns about a picture circulating of Eric in an embarrassing position, they begin to wonder if there was any foul play intended at all, and the words of the school guidance [...]

It’s been four years since eighteen-year-old Jessica Rabb went missing. Thanks to Vivian’s constant detemination to find the young woman, a new lead reveals sordid details about the missing woman’s sexual history. From sex fetishes to cults, Jessica is left with only one question: is there any way she can possibly turn her life around?

When a young soldier recently returned from Iraq disappears, Jack and Danny look into his disappearance only to learn that the soldier may have more secrets than they want to uncover.

The team searches for a man who goes missing after leaving his wife’s hair salon to deposit the day’s earnings following an argument with her. Meanwhile, Danny resists getting pulled back into the life of his convict brother who is up for parole, and Martin’s impending firearms qualifications test dredges up unsettling memories for him.

The team investigates a missing woman’s boyfriend, with whom she lived. However, they determine that he has a twin brother and quickly turn their attention to him after he is seen flirting with the missing woman at a party.

When Sam helps Martin search for his missing and terminally-ill aunt, they discover that she’s been using her nursing skills to assist other dying patients in committing suicide. His father’s Alzheimer’s diagnosis prompts Jack to attempt a reconciliation.

A father, desperate to prove that his son is innocent of murders he was convicted of committing eleven years earlier, goes missing, prompting the team to look into not only the man’s disappearance, but also the original case. Meanwhile, the family of the little girl left behind by the tragic events is determined to see [...]

The team looks for a college football coach who goes missing after being fired for his role in the team’s dismal season performance, but the investigation soon uncovers that the coach’s new policy of suspending players who had academic and behavioral issues caused the football team to repeatedly play without its main players and suffer [...]

When the team searches whether foul play was involved in the adoption of a 16-year-old girl who went missing back in 1991 shows up at the FBI offices with an article she found online, which makes her believe she was kidnapped as a young child. Meanwhile, Jack tells the team he’s moving to Chicago with [...]

The team searches for a mother and her two children, who are last seen boarding a yacht which is later found adrift in New York’s Harbor with only its dead captain aboard. Meanwhile, Malone gets ready to leave the team and move with his family to Chicago.